Motif ID: NANOG{mouse}.p2

Z-value: 1.047


Transcription factors associated with NANOG{mouse}.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NANOGchr12_+_78332610.126.7e-01Click!


Activity profile for motif NANOG{mouse}.p2.

activity profile for motif NANOG{mouse}.p2


Sorted Z-values histogram for motif NANOG{mouse}.p2

Sorted Z-values for motif NANOG{mouse}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG{mouse}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_151602787 1.454 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chrX_+_133952633 1.366 NM_001163438
LOC644538
hypothetical protein LOC644538
chr6_-_2785682 1.299 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr3_-_52542849 1.253 NT5DC2
5'-nucleotidase domain containing 2
chr8_-_27524744 1.222 NM_203339
CLU
clusterin
chr6_+_32057779 1.198 NM_007293
NM_001002029
C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr3_-_52542748 1.194 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr11_+_129444877 1.186 NM_001142276
NM_001142277
NM_001142278
NM_001642
APLP2



amyloid beta (A4) precursor-like protein 2



chr17_+_24394281 1.101 PIPOX
pipecolic acid oxidase
chr6_+_148705421 1.082 NM_015278
SASH1
SAM and SH3 domain containing 1
chr9_+_71009746 1.043 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr11_+_129445017 1.015 APLP2
amyloid beta (A4) precursor-like protein 2
chr11_+_129445002 1.005 APLP2
amyloid beta (A4) precursor-like protein 2
chr10_+_129735796 0.971 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr4_-_16509354 0.964 LDB2
LIM domain binding 2
chr11_+_129444997 0.884 APLP2
amyloid beta (A4) precursor-like protein 2
chr10_+_123912930 0.829 TACC2
transforming, acidic coiled-coil containing protein 2
chr17_+_15789147 0.774 ADORA2B
adenosine A2b receptor
chr2_-_96769502 0.764 LMAN2L
lectin, mannose-binding 2-like
chr20_+_43425153 0.753 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 read-through transcript
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr2_-_183610992 0.727 NCKAP1
NCK-associated protein 1
chr12_-_109424260 0.727 NM_016226
NM_057180
VPS29

vacuolar protein sorting 29 homolog (S. cerevisiae)

chr3_-_150578207 0.718 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr2_+_64535114 0.716 HSPC159
galectin-related protein
chr4_-_16509446 0.696 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr4_-_15686838 0.678 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr12_-_121753795 0.656 NM_177551
GPR109A
G protein-coupled receptor 109A
chr6_+_148705646 0.651 SASH1
SAM and SH3 domain containing 1
chr14_+_20226762 0.649 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_-_96769526 0.647 NM_001142292
NM_030805
LMAN2L

lectin, mannose-binding 2-like

chr4_-_16509126 0.647 LDB2
LIM domain binding 2
chr13_+_57103944 0.617 PCDH17
protocadherin 17
chr3_-_150578148 0.584 TM4SF1
transmembrane 4 L six family member 1
chr12_-_121767272 0.571 NM_006018
GPR109B
G protein-coupled receptor 109B
chr2_+_113591940 0.566 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr6_+_34312625 0.553 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr10_+_97879457 0.542 NM_014803
ZNF518A
zinc finger protein 518A
chr12_-_88270375 0.494 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr12_-_88270369 0.484 DUSP6
dual specificity phosphatase 6
chr3_-_150578103 0.473 TM4SF1
transmembrane 4 L six family member 1
chr3_+_42165740 0.471 TRAK1
trafficking protein, kinesin binding 1
chr2_-_27288518 0.461 NM_021095
SLC5A6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr3_+_173240126 0.460 FNDC3B
fibronectin type III domain containing 3B
chr4_+_166468266 0.455 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr16_+_8675904 0.451 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr11_+_129445057 0.429 APLP2
amyloid beta (A4) precursor-like protein 2
chr7_+_134226727 0.429 CALD1
caldesmon 1
chr10_+_5556923 0.427 NM_005185
CALML3
calmodulin-like 3
chr13_-_43908994 0.420 TSC22D1
TSC22 domain family, member 1
chr6_-_43531763 0.409 NM_206539
DLK2
delta-like 2 homolog (Drosophila)
chr6_+_34312633 0.403 HMGA1
high mobility group AT-hook 1
chr17_+_35629080 0.401 NM_133264
WIPF2
WAS/WASL interacting protein family, member 2
chr1_-_27113018 0.393 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr22_+_36531178 0.391 H1F0
H1 histone family, member 0
chr6_+_34312906 0.391 HMGA1
high mobility group AT-hook 1
chr2_-_85435074 0.388 NM_017750
RETSAT
retinol saturase (all-trans-retinol 13,14-reductase)
chr6_+_34312554 0.384 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr13_-_43908972 0.384 NM_006022
TSC22D1
TSC22 domain family, member 1
chr10_-_79356285 0.377 NM_004747
DLG5
discs, large homolog 5 (Drosophila)
chr13_-_43908985 0.376 TSC22D1
TSC22 domain family, member 1
chr11_-_66482366 0.375 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr1_-_152459667 0.365 C1orf43
chromosome 1 open reading frame 43
chr9_-_93225961 0.356 NM_005384
NFIL3
nuclear factor, interleukin 3 regulated
chr13_-_43908995 0.356 TSC22D1
TSC22 domain family, member 1
chr7_+_143683365 0.354 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr18_+_53967544 0.353 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr9_-_115880425 0.350 AMBP
alpha-1-microglobulin/bikunin precursor
chrX_+_107569671 0.350 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr6_-_43129583 0.347 CUL7
cullin 7
chr2_-_188021117 0.346 NM_005795
CALCRL
calcitonin receptor-like
chr19_-_60557875 0.345 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr8_-_17624304 0.341 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr1_-_152459506 0.336 C1orf43
chromosome 1 open reading frame 43
chr6_+_34312641 0.332 HMGA1
high mobility group AT-hook 1
chr7_+_121300394 0.326 NM_002851
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr11_+_120966280 0.324 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_+_7328497 0.318 POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr6_-_43129368 0.316 CUL7
cullin 7
chr22_+_36531059 0.305 NM_005318
H1F0
H1 histone family, member 0
chr16_+_8714326 0.297 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr8_+_28615062 0.295 NM_001440
EXTL3
exostoses (multiple)-like 3
chr9_+_130942029 0.292 PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr3_+_46594079 0.290 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr22_+_43527101 0.282 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr12_-_83830710 0.279 NM_001146335
NM_018057
NM_182767
SLC6A15


solute carrier family 6 (neutral amino acid transporter), member 15


chr9_-_115880281 0.278 AMBP
alpha-1-microglobulin/bikunin precursor
chr8_+_28614929 0.278 EXTL3
exostoses (multiple)-like 3
chr8_+_42871176 0.272 NM_032410
HOOK3
hook homolog 3 (Drosophila)
chr13_-_43908937 0.270 TSC22D1
TSC22 domain family, member 1
chr8_-_17624009 0.268 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr10_-_126097444 0.268 OAT
ornithine aminotransferase
chr13_-_47885018 0.266 LPAR6
lysophosphatidic acid receptor 6
chr3_+_173240107 0.264 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr3_-_56784634 0.264 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr12_+_56114724 0.263 NM_005538
INHBC
inhibin, beta C
chr14_-_93926679 0.261 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr7_+_149200937 0.255 NM_001100592
NM_145230
ATP6V0E2

ATPase, H+ transporting V0 subunit e2

chr22_+_19458378 0.254 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr8_+_9450849 0.252 NM_003747
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr1_-_43196911 0.250 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr9_-_115880494 0.249 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr3_-_140741063 0.249 RBP1
retinol binding protein 1, cellular
chr2_+_74914742 0.244 HK2
hexokinase 2
chr16_+_55261226 0.243 NM_005951
MT1H
metallothionein 1H
chr19_-_47498768 0.242 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr2_+_101874809 0.241 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr17_+_1593040 0.238 NM_001165920
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr14_+_94097513 0.235 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr6_-_43129608 0.234 NM_001168370
NM_014780
CUL7

cullin 7

chr16_+_68238460 0.234 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr3_-_95175282 0.233 PROS1
protein S (alpha)
chr10_+_102782151 0.232 SFXN3
sideroflexin 3
chr6_+_34312667 0.232 HMGA1
high mobility group AT-hook 1
chr8_-_19584373 0.232 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr10_-_126097483 0.230 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chr1_-_145712107 0.229 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr3_+_38363292 0.228 XYLB
xylulokinase homolog (H. influenzae)
chr8_+_66744659 0.226 NM_001145838
MTFR1
mitochondrial fission regulator 1
chr3_-_50335113 0.225 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr13_-_47885248 0.224 LPAR6
lysophosphatidic acid receptor 6
chr3_-_140741167 0.222 RBP1
retinol binding protein 1, cellular
chr2_+_68815416 0.219 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr12_-_56447090 0.219 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr17_-_6958282 0.213 NM_080914
ASGR2
asialoglycoprotein receptor 2
chr19_+_876984 0.211 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr11_-_72182291 0.209 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr20_-_21442663 0.209 NM_002509
NKX2-2
NK2 homeobox 2
chr7_-_30032649 0.209 NM_017946
FKBP14
FK506 binding protein 14, 22 kDa
chr8_-_27525084 0.207 NM_001171138
CLU
clusterin
chr6_+_34312979 0.206 HMGA1
high mobility group AT-hook 1
chr10_+_123913094 0.206 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr3_-_95175588 0.206 NM_000313
PROS1
protein S (alpha)
chr17_-_59437782 0.206 NM_000873
ICAM2
intercellular adhesion molecule 2
chr11_+_2378559 0.205 TSSC4
tumor suppressing subtransferable candidate 4
chr8_+_9450800 0.200 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr19_-_13074973 0.200 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr17_-_74517336 0.199 CANT1
calcium activated nucleotidase 1
chr19_+_40223249 0.199 NM_002151
NM_182983
HPN

hepsin

chr3_+_38363299 0.198 XYLB
xylulokinase homolog (H. influenzae)
chrX_+_14457340 0.197 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr17_-_37034288 0.197 NM_000422
KRT17
keratin 17
chr11_+_34599163 0.195 NM_012153
EHF
ets homologous factor
chr22_-_37966852 0.194 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chrX_-_107569256 0.192 NM_001847
COL4A6
collagen, type IV, alpha 6
chr10_+_102782156 0.190 SFXN3
sideroflexin 3
chr12_-_51298599 0.190 NM_175068
KRT73
keratin 73
chr3_+_130451119 0.189 NM_016128
COPG
coatomer protein complex, subunit gamma
chr3_+_130451160 0.187 COPG
coatomer protein complex, subunit gamma
chr2_+_62754489 0.186 NM_001142615
EHBP1
EH domain binding protein 1
chr9_+_136358134 0.186 NM_002957
RXRA
retinoid X receptor, alpha
chr10_+_63803921 0.185 NM_014951
NM_199450
NM_199451
ZNF365


zinc finger protein 365


chr19_+_40321567 0.184 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr12_+_51728999 0.183 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_15444056 0.182 NM_033083
EAF1
ELL associated factor 1
chr19_-_2998632 0.179 NM_001144761
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr1_-_148508030 0.174 NM_001077628
NM_016022
APH1A

anterior pharynx defective 1 homolog A (C. elegans)

chr19_-_13074669 0.173 LYL1
lymphoblastic leukemia derived sequence 1
chr3_-_15443985 0.171 NM_152396
METTL6
methyltransferase like 6
chr8_+_31616809 0.168 NM_013962
NRG1
neuregulin 1
chr17_-_31337798 0.167 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr3_-_152517204 0.167 NM_023915
GPR87
G protein-coupled receptor 87
chr11_-_66396178 0.166


chr19_-_59019240 0.165 NM_144687
NLRP12
NLR family, pyrin domain containing 12
chr6_-_46997579 0.163 NM_001098518
GPR116
G protein-coupled receptor 116
chr2_-_136590210 0.162 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr4_+_154345039 0.160 NM_015271
TRIM2
tripartite motif containing 2
chr17_+_19492427 0.160 NM_000382
NM_001031806
ALDH3A2

aldehyde dehydrogenase 3 family, member A2

chr17_-_35327318 0.159 NM_018530
GSDMB
gasdermin B
chr6_+_87921980 0.158 NM_015021
ZNF292
zinc finger protein 292
chrX_+_70351773 0.156 NM_001097642
GJB1
gap junction protein, beta 1, 32kDa
chrX_-_102828238 0.156 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chr9_+_138680064 0.156 EGFL7
EGF-like-domain, multiple 7
chr17_-_59817654 0.154 PECAM1
platelet/endothelial cell adhesion molecule
chr17_-_59817575 0.154 PECAM1
platelet/endothelial cell adhesion molecule
chr4_+_19864332 0.152 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr12_-_14887648 0.151 NM_021071
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr16_+_19032744 0.151 NM_001034841
ITPRIPL2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr16_-_31054563 0.151 NM_002773
PRSS8
protease, serine, 8
chr17_-_36346240 0.150 KRT23
keratin 23 (histone deacetylase inducible)
chr11_+_69165119 0.150 CCND1
cyclin D1
chr19_-_10625449 0.150 LOC147727
hypothetical LOC147727
chr20_+_43953606 0.148 CTSA
cathepsin A
chr3_-_122951200 0.148 NM_004487
GOLGB1
golgin B1
chr3_+_31549123 0.148 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr19_-_63565890 0.146 NM_198458
ZNF497
zinc finger protein 497
chr19_-_55062611 0.146 NM_007254
PNKP
polynucleotide kinase 3'-phosphatase
chr6_-_43592679 0.142 NM_015388
YIPF3
Yip1 domain family, member 3
chr16_+_29994843 0.142 NM_002720
PPP4C
protein phosphatase 4, catalytic subunit
chr14_-_93859394 0.141 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr6_-_41238798 0.138 TREM2
triggering receptor expressed on myeloid cells 2
chr20_-_61028263 0.137 DIDO1
death inducer-obliterator 1
chr2_+_234209838 0.136 NM_019075
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr10_+_114699953 0.136 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr10_-_1024280 0.132 LOC100288619
hypothetical LOC100288619
chr22_-_35114001 0.131 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr1_-_79244948 0.131 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr7_+_73506047 0.130 NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
chr11_-_56761250 0.129 NM_005161
APLNR
apelin receptor
chr17_-_74517417 0.128 NM_001159772
NM_001159773
NM_138793
CANT1


calcium activated nucleotidase 1


chr16_+_29994818 0.127 PPP4C
protein phosphatase 4, catalytic subunit

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.